objective: because of the necessity of more effective treatments for the nervous system injuries and considering the role of survivin in cellular proliferation and apoptotic cell death, we have monitored survivin gene expression changes during the course of regeneration in injured sciatic nerves and also l4-l6 segments of spinal cord. materials and methods: we used adult male nmri mice as a mo...

Background: Anatomical and histological studies of the spinal cord have always garnered anatomists’ attention because of their high importance in various fields of veterinary medicine, zoology and behavioral science. OBJECTIVES: This work was conducted to understand the detailed histomorphometric aspects of the spinal cord of Indian gray mongoose (Herpestes edwardsii). METHODS: Six adult Indian...

in this study, the vertical, transverse and oblique diameters of the spinal cord segments (c1, c6, c12, c18, t1, t4, l1, l4, l6 and l8) and the ratio of gray matter to white matter in chick (l month) and adult (18 months) male ostriches, each group consisted of 3 animals, were measured with standard micrometric method using 6 μm thick sections by light microscope. with advancement of age, the r...

In this study, the vertical, transverse and oblique diameters of the spinal cord segments (C1, C6, C12, C18, T1, T4, L1, L4, L6 and L8) and the ratio of gray matter to white matter in chick (l month) and adult (18 months) male ostriches, each group consisted of 3 animals, were measured with standard micrometric method using 6 μm thick sections by light microscope. With advancement of age, the r...

introduction: electrophysiologycal histological methods were for studing the anatomical distribution of group i and ii muscle afferent in the lumbosacral segments of wistar rat spinal cord. material and methods: quadriceps, deep proneal, hamestring, gastrocnemius-soleus, tibialis posterior, plantaris, flexor digitorum longus and popliteus muscle nerves were dissected and mounted on surface elec...

Introduction: Nasopharyngeal carcinoma is one of the most common malignancies in the head and neck region and radiotherapy is its treatment of choice. In spite of the fact that it is widely used, due to the presence of many sensitive organs or tissues in this region, patients may suffer from a wide range of side effects. One such sensitive tissue is the spinal cord. If the absorbed dose to spin...

Accurate identification of spinal cord segments in relation to vertebral landmarks is essential to surgery aimed at experimental spinal cord injury. We have analyzed a complete series of high-resolution magnetic resonance (MR) images from the mouse spine in order to delineate the boundaries of spinal cord segments in relation to vertebral landmarks. The resulting atlas can be used to plan exper...

introduction: nasopharyngeal carcinoma is one of the most common malignancies in the head and neck region and radiotherapy is its treatment of choice. in spite of the fact that it is widely used, due to the presence of many sensitive organs or tissues in this region, patients may suffer from a wide range of side effects. one such sensitive tissue is the spinal cord. if the absorbed dose to spin...

Wall and Shortland (1991) have shown that afferent fibers entering the cord in thoracic and lumbar roots of adult rats have branches that may penetrate up to 11 segments caudally from the root entry zone. We have investigated the extent of branching and conduction velocities of ascending and descending branches of lumbar and thoracic primary afferents in isolated spinal cords of adult hamsters ...

Background: Oligodendrocyte cell death is among the important features of spinal cord injury, which appears within 15 min and occurs intensely for 4 h after injury, in the rat spinal contusion model. Accordingly, the number of oligodendrocytes progressively reduced within 24 h after injury. Administration of oligodendrocyte-like cells (OLCs) into the lesion area is one of the approaches to coun...